

JDawnInk/Digital Imaginative and prescient Vectors/Getty Pictures
For purchasers utilizing a telehealth web site to get cheaper variations of well-liked weight problems medicine, the low costs turned out to be too good to be true.
Clients of Zappy Well being inform NPR they had been drawn to the net supplier by its low costs, its lack of subscription charges and its helpful smartphone app with a chat function for sufferers to speak to at least one one other throughout their weight-loss journeys.
The Zappy chat was finally what number of prospects first discovered that Ousia Pharmacy — one in all a number of pharmacies that equipped Zappy with compounded weight problems medicine — did not have a required license, one which ensured the medicine had been produced in accordance with security and efficiency requirements.
Compounded medicine that Zappy and different telehealth websites promote aren’t generics. As a substitute, they’re basically copies of the name-brand medicine made by specialised pharmacies. The Meals and Drug Administration permits this sort of compounding throughout drug shortages.
Compounding pharmacies are regulated on the state stage. Ousia, in Spring Hill, Fla., did not have what’s known as a sterile compounding license. The weight problems medicine made by compounding pharmacies are given by injection, so consideration to sterile manufacturing is important to keep away from contamination that would trigger infections.
Zappy did not discover out about Ousia’s licensing drawback till December and it ceased its roughly three-month relationship with the pharmacy on Dec.13, Zappy’s founder Dr. Michel Choueiri instructed NPR in an e-mail after a broadcast model of this story aired. He known as Zappy “the largest victims of this example,” and mentioned that it has left the corporate in “extreme monetary and reputational wreck.”
Some Zappy prospects NPR spoke with came upon about the issue on Reddit.
Laura Franzese, in Portland, Ore., discovered concerning the licensing drawback after spending $1,000 on a bulk order of tirzepatide from Zappy that arrived with Ousia labels. (Tirzepatide is the energetic ingredient in Eli Lilly’s weight problems drug Zepbound.) She’d been taking the medicine already, from a neighborhood supplier, and known as them “life-changing,” however made the swap to Zappy hoping to economize.
“I purchased three months’ price of medication from this firm,” she says. Now she’s afraid to make use of the medicine. “It was a giant funding.”
Individuals energetic on Reddit instructed NPR that Zappy deleted the unique consumer publish in its app chat discussion board about Ousia’s lack of the right license. Choueiri says Zappy publicly apologized in the identical discussion board and solely eliminated the publish whereas it was verifying the declare.
Ousia could not be reached for remark.

When Laura Franzese began with compounded tirzepatide at a neighborhood medical spa, she misplaced 20 kilos in 16 weeks. “It giving me one thing that my physique clearly wanted,” she says. But it surely was costly. She found she might get a lower cost from Zappy Well being.
Laura Franzese
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Laura Franzese
For many individuals who’ve turned to on-line telehealth corporations to seek out compounded weight problems medicine, they are saying they would like to take the brand-name medicine, however it is not an possibility for them. They are saying Novo Nordisk’s Wegovy and Eli Lilly’s Zepbound, aren’t lined by their insurance coverage. And paying the complete sticker value – greater than $1,000 a month – is simply too costly.
Compounding pharmacies fill a niche for sufferers like this. They have been part of the well being care panorama for many years, making ready customized medicines for individuals who want them, however booming demand for weight-loss medicine — and ensuing brand-name shortages — has introduced them into new prominence.
Even some individuals who have medical insurance protection for weight problems medicine say they flip to telehealth and compounding as a result of they could not reliably discover the brand-name medicine in native pharmacies.
However the state of affairs with Ousia reveals the pitfalls of navigating the world of on-line compounded weight problems medicine, which incorporates reliable companies in addition to some unlicensed or unregistered ones. It may be troublesome for customers to inform the distinction, or belief the standard of the weight problems medicine they’re shopping for.
Searching for a deal, discovering confusion
For Zappy prospects the issues got here as a shock.
Eric Bishop, an IT skilled in Salt Lake Metropolis, Utah, was searching for a manner to purchase extra tirzepatide without delay, fearing that the official finish to the Zepbound scarcity would imply the finish of the compounded model. He had been filling his prescription at a neighborhood brick-and-mortar compounding pharmacy, however turned to Zappy to purchase a stockpile.
He did not know which pharmacy could be fulfilling the order by Zappy till after he paid. “They did not give me a selection,” he says.
Bishop had simply gotten his 9-month provide of tirzepatide price $2,700 from Zappy when customers on the Zappy app blew the whistle on Ousia.
“That is after I began seeing issues within the chat,” he says of the app’s affected person discussion board function. “So I bounced over to Reddit.”
Based on a criticism filed by the Florida Division of Well being on Dec. 5, Ousia utilized for a sterile compounding license in March 2024, however it was by no means granted. When state regulators inspected the ability later that yr in August, they found that it was compounding medicines anyway. As well as, inspectors famous that Ousia was improperly storing medicine that wanted to be refrigerated and never conserving correct data for medicine it allotted.
The Florida Division of Well being didn’t reply to requests for touch upon this story. In an e-mail to NPR, Zappy’s founder, Choueiri, mentioned the division did not disclose Ousia’s drawback “in a well timed method.”
Bishop could not imagine what he was studying.
“I am hastily, you recognize, about prepared to start out taking my treatment and I am like, I now not have any confidence in what I’ve,” Bishop says. “And I would both need my a refund or I desire a substitute for what I’ve.”
Eric Bishop helps run a Fb group for individuals who received Ousia vials from Zappy Well being and try to get their a refund. Since Ousia gave up its common pharmacy license on Jan. 31, he says some folks have been extra profitable.
Eric Bishop
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Eric Bishop
One other Zappy affected person, Nicole Drong, in Minneapolis, Minn., says she was shocked when vials marked “Ousia” arrived at her residence. “I didn’t know the identify of the pharmacy till I received a bundle. And I used to be like, ‘Effectively, that is bizarre. I assumed it was going to say Zappy on it.’ “
Then in December, she seen the Zappy app was sending her much more notifications than ordinary from the affected person discussion board. Phrase was out that Ousia did not have a sterile compounding license.
“I sort of really feel silly, I assume,” Drong says. She says she was ” simply blindly placing belief on this pharmacy … How usually do you ever must double-check your treatment? Like, if I am going get my antidepressants from Walgreens, do I’ve to double-check to verify there’s not something additional in my bottle of capsules?”
Choueiri, Zappy’s founder, says sufferers have the chance to cancel as soon as they study which pharmacy is fulfilling their order, and it has responded to affected person suggestions to be extra clear with prospects up entrance.
Confusion and no refunds
The bureaucratic particulars of licensing will be opaque to customers. However these licenses matter, says Scott Brunner, who leads the commerce group of compounding pharmacists, the Alliance for Pharmacy Compounding. Ousia pharmacy wasn’t a member, he says.
He known as not having a sterile compounding license the place one is required “egregious.”
“I’d not take a drug that has been allotted to that affected person from a pharmacy that has been discovered to be in violation of its state license legislation,” he says.
Choueiri, did a TikTok reside on Jan. 15, the place he mentioned Zappy was “made conscious of the criticism” and needed to let the method play out. He added that his relations had been taking the Ousia drugs, too, and he was additionally fielding questions from them.
“It isn’t counterfeit?” he mentioned, studying questions as they got here in. “Yeah, no. No, it isn’t counterfeit. Um no, no. The quick reply is not any, however I am not going to go down the authorized litigation right here.”
At first, Zappy instructed folks they may fill out a Google kind to get a refund or substitute vials, however prospects inform NPR that nothing got here of it but. For a time, Zappy additionally instructed prospects to ask Ousia for a refund as a substitute.
On Jan. 31, 2025, Ousia voluntarily relinquished its common pharmacy license, Florida data present. Now, the pharmacy’s telephone quantity goes to voicemail and its web site is down.
Requested what Zappy is now advising its sufferers to do with their Ousia vials, Choueiri wrote to NPR: “As at all times, Zappy is a platform that connects sufferers to inexpensive care however doesn’t substitute the position of medical suppliers or pharmacists. Selections about treatment use ought to at all times be made in session with a licensed healthcare skilled, and defer these conversations to the suppliers of care.”

Zappy Well being adverts on Fb and Instagram promote its weight-loss program, which entails connecting sufferers to on-line suppliers and sending them low-cost weight problems medicine made by compounding pharmacies.
Zappy/Pictures screenshot and compiled by NPR
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Zappy/Pictures screenshot and compiled by NPR
Choueiri is a medical physician. On its web site, Zappy touts that its weight-loss plans “are customized by medical doctors.”
Based on Zappy’s phrases of service, the doctor-patient relationship is not between Zappy and its customers. It is between the suppliers who do digital appointments and prescribing on Zappy and the Zappy prospects. And the corporate “disclaims any legal responsibility for the medical or pharmaceutical providers offered by its platform.”
Recognizing purple flags
Whereas the Ousia state of affairs is unlucky for the sufferers concerned, it is an instance of the regulatory system working the way in which it is presupposed to, says Brunner.
The Nationwide Affiliation of Boards of Pharmacy says it is exhausting to know what number of on-line retailers are providing compounded weight problems medicine which can be made with out the right license or registration. State pharmacy boards oversee most compounding pharmacies across the nation, but when a pharmacy is not registered or licensed in a state the place it is delivery merchandise, it may be exhausting to trace.
Betty Jones, compliance senior supervisor of the accreditation and inspection packages at NABP, says customers can defend themselves by looking for purple flags. As an illustration, you must at all times know which pharmacy is filling your prescription, they usually’re required to supply counseling.
“If they don’t seem to be offering you that provide of affected person counseling otherwise you’re calling into that pharmacy they usually do not assist you to, you recognize, be progressed to a pharmacist the place you possibly can ask questions, that may be one thing that I’d name a purple flag.”
She says costs which can be too low and pharmacies that do not ask for a prescription must also set off alarm bells.
Potential prospects must also be capable to confirm {that a} pharmacy is licensed, since these are public data obtainable on-line in most states. And to dispense to you, meaning the pharmacy must be licensed in your state, too – not simply the one the place it is positioned.
Bishop, the Zappy buyer in Utah, says he helped arrange a Fb group for folks to assist them determine the right way to get their a refund. Clients say they have not been in a position to get refunds.
Choueiri says Zappy’s low costs imply it does not have a lot cash left over after paying pharmacies and suppliers, and “Zappy doesn’t management the funds essential to situation refunds.”
The Fb group has grown to greater than 600 folks. Its members have even helped report new info to the Florida Division of Well being, Bishop says. “We’re only a neighborhood simply sort of serving to one another out.”
Lots of the group members’ banks initially declined to reverse their bank card transactions with Zappy. That is began to alter since Ousia relinquished its license, Bishop says. “Really, some banks are even opening disputes that they closed beforehand.”
Zappy’s nonetheless promoting to prospects, however Bishop says he is not shopping for from the corporate once more. He is again on compounded tirzepatide from his native pharmacy.